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Skincare chemists Gloria & Victoria’s weekly conversation on all things skincare science.
The podcast covers notable skincare news, decoding outrageous claims, demystifying the overwhelming product landscapes, and answering your burning skincare questions. Tune in if you might need help building a skincare routine, finding a serum that’ll ACTUALLY deliver, or just want to have a few laughs on some of the crazy things you see in skincare.
Episodes
Tuesday Oct 21, 2025
Tuesday Oct 21, 2025
We review 10 popular East and West barrier creams from Aestura, Dr. Jart, Dieux, Skinceuticals, La Roche Posay, and more. We break down everything from texture and finish for different skin types to occlusives like petrolatum and dimethicone, humectants like glycerin, and clinical claims. We also look at which creams are best for "suffering" vs. generally healthy skin
00:00 | 10 Barrier Creams: East vs. West Product Lineup
02:44 | How much do Barrier Creams cost? Price Buckets
03:51 | What are the different Barrier Cream textures for dry and oily skin?
09:25 | Moisturizer Residue: How long does the cream's finish last?
16:22 | Pilling Potential: Which barrier creams are prone to pilling?
18:15 | How do chemists evaluate a barrier cream? Key ingredients
18:52 | Heavy-handed vs. Lightweight Occlusives in Barrier Creams
21:20 | Glycerin and Humectants in Barrier Creams: What position matters?
25:38 | Clinical Highlights: Dieux, Dr. Jart, and Aestura claims explained
31:17 | Barrier Cream Recommendations for Suffering vs. Healthy Skin
Products Discussed this 2025 Podcast Season *a small portion of your purchase through these links goes to feeding a chemist. https://shopmy.us/collections/1280514
Recommended 30 for 30 Sunscreens 2025 *a small portion of your purchase through these links goes to feeding a chemist. https://shopmy.us/collections/1766357
Product Shoutout: Blank Slate Gentle Gel Cleanser https://chemistconfessions.com/products/blank-slate-cleanser
Enrichment Content: Sunscreen Layering Guide https://www.youtube.com/watch?v=IQ0Dlb0WXvc
Do We Absorb Sunscreen Filters into Our Bloodstreams? https://chemistconfessions.com/blogs/controversy-corner-do-we-absorb-sunscreen-filters-into-our-bloodstreams
Follow us: IG: / chemist.confessions INTERWEB: https://chemistconfessions.com/ TIKTOK: https://www.tiktok.com/@chemistconfes...
Skincare questions for the podcast? Leave your question in the comments and it could be featured in our next episode! #chemistconfessions #skincarescience #chemistconfessionspodcast #skincarehack
Monday Oct 13, 2025
Monday Oct 13, 2025
We put three 10% OTC sulfur products to the test! Kate Somerville, the Ordinary, Vichy, and De La Cruz Lab have four completely different takes on sulfur. The chemists discuss which product is the best to use as an acne spot treat!
Products Discussed this 2025 Podcast Season
*a small portion of your purchase through these links goes to feeding a chemist.
https://shopmy.us/collections/1280514
Product Shoutout:
The Specialist: https://chemistconfessions.com/products/the-specialist-exfoliating-treatment
Enrichment Content:
EP153: OTC Sulfur for Acne is Kinda Weird!
https://www.youtube.com/watch?v=6cPB2eUtYpY&list=PLldQkxjc7bYnFkUtOw8Y07yCyBnaF4ddx&index=2
From the Blog: The Chemists’ Comprehensive Guide to Acne Pt. 1
https://chemistconfessions.com/blogs/the-chemists-comprehensive-guide-to-acne-pt-1
00:00 | Sulfur Products Review: Which 10% Sulfur Acne Treatment is Best?
00:39 | What are the selection criteria for the 4 sulfur products?
01:22 | Price comparison of The Ordinary, Vichy, Kate Somerville, and De La Cruz sulfur products
02:48 | How does a dry-skin representative use a drying sulfur spot treatment?
03:38 | Which sulfur product has a classic drying, high absorption lotion texture?
04:00 | The problem with Kate Somerville's isopropyl alcohol-based drying lotion
06:30 | Ranking sulfur products by "rotten egg smell"—which one smells the most?
08:46 | Chemist Notes: Which oil-absorbing powders are in the sulfur formulas?
11:13 | Which sulfur products contain additional acne actives like Glycolic or Salicylic Acid?
14:11 | Is sulfur a long-term preventative acne ingredient or just a spot treat?
Follow us:
IG: https://www.instagram.com/chemist.con...
INTERWEB: https://chemistconfessions.com/
TIKTOK: https://www.tiktok.com/@chemistconfes...
Skincare questions for the podcast?
Leave your question in the comments and it could be featured in our next episode! #chemistconfessions #skincarescience #chemistconfessionspodcast #skincarehack
Monday Oct 06, 2025
Monday Oct 06, 2025
In paid partnership with VT! VT has given us insider access to the R&D behind their viral Reedle Skincare. In thanks to our community’s curiosity, they’ve decided to share the research behind their reedles, what makes them special, and all the testing they’ve done behind this product line. The chemists also share their experience and recommendation using this uniquely prickly but soothing? Kbeauty serum.
Products Discussed this 2025 Podcast Season
*A small portion of your purchase through these links goes to feeding a chemist. (Thank you!)
https://shopmy.us/shop/collections/1280514
Enrichment Content:
EP 128: Our Deep Dive into Spicules (Non-paid/non-gifted)
https://www.youtube.com/watch?v=acn8V6-4_Uk&t=61s
EP 129: VT’s Reedle Shot 50 vs. 100 (Non-paid/non-gifted)
https://www.youtube.com/watch?v=O-BwdlFYFU0&t=1s
Follow us:
INTERWEB: https://chemistconfessions.com/
TIKTOK: https://www.tiktok.com/@chemistconfes...
Skincare questions for the podcast?
Leave your question in the comments and it could be featured in our next episode! #chemistconfessions #skincarescience #chemistconfessionspodcast #skincarehack
Wednesday Oct 01, 2025
Wednesday Oct 01, 2025
We take a deep dive into the science behind Sulfur, a very old and historically prevalent ingredient for acne. We discuss its nonmetal clay origins and characteristic scent, often described as rotten eggs , or like "if a clay farted". The episode covers its classification as an OTC acne ingredient , its proposed catalytic and oil-absorbing mechanisms , and the challenges in its topical formulation, such as particle size. We also look at old-school research, including a study on 10% Sulfur + 4% Niacinamide drying lotion , and offer realistic expectations: Sulfur is best used as a spot treatment for quick fixes, not for long-term overall breakout reduction
Products Discussed this 2025 Podcast Season
*a small portion of your purchase through these links goes to feeding a chemist.
https://shopmy.us/collections/1280514
Recommended 30 for 30 Sunscreens 2025
*a small portion of your purchase through these links goes to feeding a chemist.
https://shopmy.us/collections/1766357
Product Shoutout:
Blank Slate Gentle Gel Cleanser
https://chemistconfessions.com/products/blank-slate-cleanser
Enrichment Content:
Sunscreen Layering Guide
https://www.youtube.com/watch?v=IQ0Dlb0WXvc
Do We Absorb Sunscreen Filters into Our Bloodstreams?
https://chemistconfessions.com/blogs/controversy-corner-do-we-absorb-sunscreen-filters-into-our-bloodstreams
Follow us:
IG: / chemist.confessions
INTERWEB: https://chemistconfessions.com/
TIKTOK: https://www.tiktok.com/@chemistconfes...
Skincare questions for the podcast?
Leave your question in the comments and it could be featured in our next episode! #chemistconfessions #skincarescience #chemistconfessionspodcast #skincarehack
Wednesday Sep 17, 2025
Wednesday Sep 17, 2025
Everyone at some point in their lives will experience skin irritation. From overeager retinoid use to skin deciding to do a complete 180° just because. When skin is angry, troubleshooting your routine can start to feel stressful and overwhelming . The chemists review why skin reacts the way it does and best practices on how to appease unhappy skin and recalibrate back to your original healthy skin.
Products Discussed this 2025 Podcast Season
*A small portion of your purchase through these links goes to feeding a chemist. (Thank you!)
https://shopmy.us/collections/1280514
Product Shoutout:
Aquafix Soothing Hydrating Serum
https://chemistconfessions.com/products/aquafix-hydrating-water-gel
Enrichment Content:
Navigating Plant Extracts: A Guide
https://chemistconfessions.com/blogs/botanicals-a-skincare-ingredient-jungle
EP136: Can You Just Use Water to Cleanse Your Face?
https://www.youtube.com/watch?v=8GDay3OeG7Q
Follow us:
IG: https://www.instagram.com/chemist.confessions/
INTERWEB: https://chemistconfessions.com/
TIKTOK: https://www.tiktok.com/@chemistconfessions?lang=en
Skincare questions for the podcast?
Leave your question in the comments and it could be featured in our next episode! #chemistconfessions #skincarescience #chemistconfessionspodcast #skincarehack
Tuesday Sep 09, 2025
Tuesday Sep 09, 2025
We put popular hypochlorous acid sprays to the test! Tower 28, Prequel, and Magic Molecule. Do they live up to the hype for acne, redness, and barrier support? Here’s the chemists’ breakdown.
Products Discussed this 2025 Podcast Season
*a small portion of your purchase through these links goes to feeding a chemist.*
[https://shopmy.us/collections/1280514](https://shopmy.us/collections/1280514)
Recommended 30 for 30 Sunscreens 2025
*a small portion of your purchase through these links goes to feeding a chemist.*
[https://shopmy.us/collections/1766357](https://shopmy.us/collections/1766357)
Product Shoutout:
Blank Slate Gentle Gel Cleanser
[https://chemistconfessions.com/products/blank-slate-cleanser](https://chemistconfessions.com/products/blank-slate-cleanser)
Enrichment Content:
Sunscreen Layering Guide
[https://www.youtube.com/watch?v=IQ0Dlb0WXvc](https://www.youtube.com/watch?v=IQ0Dlb0WXvc)
Do We Absorb Sunscreen Filters into Our Bloodstreams?
[https://chemistconfessions.com/blogs/controversy-corner-do-we-absorb-sunscreen-filters-into-our-bloodstreams](https://chemistconfessions.com/blogs/controversy-corner-do-we-absorb-sunscreen-filters-into-our-bloodstreams)
Follow us:
IG: / chemist.confessions
INTERWEB: [https://chemistconfessions.com/](https://chemistconfessions.com/)
TIKTOK: [https://www.tiktok.com/@chemistconfes](https://www.tiktok.com/@chemistconfes)...
Skincare questions for the podcast?
Leave your question in the comments and it could be featured in our next episode! #chemistconfessions #skincarescience #chemistconfessionspodcast #skincarehack
Thursday Aug 28, 2025
Thursday Aug 28, 2025
Hypochlorous acid is the trending skincare ingredient for acne, eczema, and irritated skin...... but does it really work?
Products Discussed this 2025 Podcast Season
a small portion of your purchase through these links goes to feeding a chemist.
https://shopmy.us/collections/1280514
Tuesday Aug 19, 2025
Tuesday Aug 19, 2025
From $20 drugstore finds to $185 luxury formulas, We break down Vitamin C skincare products, textures, and ingredient lists to help you choose what really works for hyperpigmentation, hydration, and beyond.
Products Discussed this 2025 Podcast Season
*a small portion of your purchase through these links goes to feeding a chemist.
https://shopmy.us/collections/1280514
Product Shoutout:
Blank Slate Gentle Gel Cleanser https://chemistconfessions.com/products/blank-slate-cleanser
Enrichment Content:
EP144: Is 3-o-ethyl ascorbic acid a worthy vitamin C derivative?
https://www.youtube.com/watch?v=X9wfbFIUIJg
From the Blog: Which Vitamin C Derivative is Best for My Skin
https://chemistconfessions.com/blogs/which-vitamin-c-derivative-is-the-best-for-my-skin
Follow us:
IG: https://www.instagram.com/chemist.confessions/?hl=en
INTERWEB: https://chemistconfessions.com/
TIKTOK: https://www.tiktok.com/@chemistconfessions?lang=en
Skincare questions for the podcast?
Leave your question in the comments and it could be featured in our next episode! #chemistconfessions #skincarescience #chemistconfessionspodcast #skincarehack
Wednesday Aug 06, 2025
Wednesday Aug 06, 2025
Is tetrahexyldecyl ascorbate (aka. THD ascorbate) a more stable, more exciting form of vitamin C, or just another quirky chemical cousin? We unpack the science, separate facts from marketing fluff, and reveal what this ingredient really does for your skin.
Products Discussed this 2025 Podcast Season
*a small portion of your purchase through these links goes to feeding a chemist.
https://shopmy.us/collections/1280514
Product Shoutout:
Blank Slate Gentle Gel Cleanser https://chemistconfessions.com/products/blank-slate-cleanser
Enrichment Content:
EP144: Is 3-o-ethyl ascorbic acid a worthy vitamin C derivative?
https://www.youtube.com/watch?v=X9wfbFIUIJg
From the Blog: Which Vitamin C Derivative is Best for My Skin
https://chemistconfessions.com/blogs/which-vitamin-c-derivative-is-the-best-for-my-skin
Follow us:
IG: https://www.instagram.com/chemist.confessions/?hl=en
INTERWEB: https://chemistconfessions.com/
TIKTOK: https://www.tiktok.com/@chemistconfessions?lang=en
Skincare questions for the podcast?
Leave your question in the comments and it could be featured in our next episode! #chemistconfessions #skincarescience #chemistconfessionspodcast #skincarehack
Friday Jul 25, 2025
Friday Jul 25, 2025
It’s the last sunscreen episode of 2025 (we promise!). The chemists have been mulling over all of the recent sunscreen drama. Ultimately, they’ve decided that the most constructive way to address everyone’s concerns is to walk everyone through how to properly shop for sunscreens in 2025. In this guided tour of sunscreens, they will also address concerns on SPF boosters and even how to process the concerning results published by Choice.
00:20 | Chemist Confessions Podcast: Addressing the Sunscreen Drama
01:00 | How to Shop for Sunscreen
01:49 | Method to Shop for Sunscreen: Addressing Concerns and Finding Confidence
02:29 | Starting Point: Chemical Fluid or Lotion Formulas
03:17 | Asian or EU Sunscreens (Chemical)
05:29 | Why are US Sunscreens Different? (Texture Discussion)
07:41 | When to Choose Mineral Sunscreens (Acne, Irritation, Sensitivity)
08:40 | Mineral Sunscreen Controversy: Are "Mineral" Sunscreens Truly Mineral?
09:58 | Understanding UV Boosters in Sunscreen Formulas
12:01 | Quirky Traits of Mineral Sunscreens: White Cast and Powdery Formulas
30 for 30 Sunscreen Challenge Compiled Summary
*a small portion of your purchase through these links goes to feeding a chemist.
https://shopmy.us/collections/1766357
Other products discussed this 2025 Podcast Season
https://shopmy.us/collections/1280514
Product Shoutout:
Blank Slate Gentle Gel Cleanser
https://chemistconfessions.com/products/blank-slate-cleanser
Enrichment Content:
Can You Layer Foundation With Sunscreen
https://www.youtube.com/watch?v=IQ0Dlb0WXvc&t=1356s
Chemists’ Complete Sunscreen Review Guide
https://chemistconfessions.com/blogs/how-to-best-use-cleansers
Follow us:
IG: https://www.instagram.com/chemist.confessions/
INTERWEB: https://chemistconfessions.com/
TIKTOK: https://www.tiktok.com/@chemistconfes…