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Skincare chemists Gloria & Victoria’s weekly conversation on all things skincare science.
The podcast covers notable skincare news, decoding outrageous claims, demystifying the overwhelming product landscapes, and answering your burning skincare questions. Tune in if you might need help building a skincare routine, finding a serum that’ll ACTUALLY deliver, or just want to have a few laughs on some of the crazy things you see in skincare.
Episodes
Wednesday Apr 01, 2026
Wednesday Apr 01, 2026
We are diving back into the "rumor mill" of the retinoid world! Is Retinal actually better than Retinol, or is it just better marketing?
In this episode, we revisit the Retinol vs. Retinal debate with new 2026 data. We break down what the evidence says about the retinoid conversion pathway into retinoic acid. We look at the latest clinical evidence to help you decide if it’s time to switch your anti-aging active or stay the course with your current skincare routine.
Episode Timestamps
0:00 - Intro: Revisiting the Retinoid Rumor Mill
1:34 - Why Retinal (Retinaldehyde) is Growing in Popularity
2:01 - The Science of Retinoic Acid Conversion Steps
5:30 - What the Data Shows (Retinol vs. Retinal ex vivo Conversion)
9:15 - Retinal vs. Retinol: Potency & Efficacy Realities
14:40 - Is Retinal Actually Gentler? (Irritation & Skin Barrier)
18:20 - Debunking High-Concentration Retinoid Myths
23:55 - Reviewing Recent Retinal Product Launches
28:10 - How to Choose: Retinol or Retinal for your Skin Type?
36:22 - Final Verdict: Should You Switch Your Active?
Resources & Mentions
Retinal vs Retinol on the CC Blog: https://chemistconfessions.com/blogs/retinal-is-it-better-than-retinol
Retinol vs Tretinoin: https://chemistconfessions.com/blogs/tretinoin-vs-retinol
Follow us on IG : @chemist.confessions
#chemistconfessions #retinal #retinol #skincarescience #antiaging #retinaldehyde #skincareroutine
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