Chemist Confessions

CHECK OUT DOUBLE PLAY!: https://chemistconfessions.com/products/double-play-retinol-face-eye-treatment

We are wrapping up our hyperpigmentation series by diving into the science of resorcinol and its various derivatives. We explore the history of this "ancient" molecule, its uses in treatments like designer peels and acne prescriptions, and why the industry has shifted toward modern derivatives to avoid skin irritation.

00:21 | Part 2: Continuing our Resorcinol Series 
00:35 | What is Hexylresorcinol? 
00:49 | Hexylresorcinol vs. 2% Hydroquinone: The Study Breakdown 
01:07 | Testing Parameters: 1% Hexylresorcinol Concentration 
01:37 | Analyzing the Results: Expert Grading and Data 
01:53 | 12-Week Results: Significant Improvements in Pigmentation 
02:03 | Comparing Performance to Hydroquinone 
25:22 | Major Formulation Challenges with Resorcinols
25:33 | Conclusion and What’s Coming Next

Do We Absorb Sunscreen Filters into Our Bloodstreams? https://chemistconfessions.com/blogs/controversy-corner-do-we-absorb-sunscreen-filters-into-our-bloodstreams 

Follow us: IG:   / chemist.confessions   INTERWEB: https://chemistconfessions.com/ TIKTOK: https://www.tiktok.com/@chemistconfes...

Skincare questions for the podcast? Leave your question in the comments and it could be featured in our next episode! #chemistconfessions #skincarescience #chemistconfessionspodcast #skincarehack

CHECK OUT DOUBLE PLAY!: https://chemistconfessions.com/products/double-play-retinol-face-eye-treatment

We are wrapping up our hyperpigmentation series by diving into the science of resorcinol and its various derivatives. We explore the history of this "ancient" molecule, its uses in treatments like designer peels and acne prescriptions, and why the industry has shifted toward modern derivatives to avoid skin irritation.

01:28 | What is resorcinol? 
01:50 | Resorcinol in acne treatments and designer peels 
02:13 | Why is resorcinol used in hair dyes? 
02:33 | The shift toward resorcinol derivatives for skin safety 
02:54 | EU SCC regulations on resorcinol concentrations 
22:30 | Hyperpigmentation serum scenarios and skin discomfort
23:05 | Preview: Hexylresorcinol and Diamond Oil

Do We Absorb Sunscreen Filters into Our Bloodstreams? https://chemistconfessions.com/blogs/controversy-corner-do-we-absorb-sunscreen-filters-into-our-bloodstreams 

Follow us: IG:   / chemist.confessions   INTERWEB: https://chemistconfessions.com/ TIKTOK: https://www.tiktok.com/@chemistconfes...

Skincare questions for the podcast? Leave your question in the comments and it could be featured in our next episode! #chemistconfessions #skincarescience #chemistconfessionspodcast #skincarehack

We are back for a follow-up to our glutathione deep dive! We review five specific glutathione-heavy products, four from the K-beauty world and one popular Amazon find, to see if they truly deliver on their antioxidant and brightening claims.

00:00 | Intro: Hashtags & antioxidant claims
00:24 | Welcome back to Chemist Confessions Podcast
00:30 | Glutathione deep dive follow-up
00:56 | Product lineup: 4 K-beauty + 1 Paula’s Choice
02:05 | Price points & supply differences
03:40 | Texture notes: neutral, not hydrating
05:03 | Fragrance issues & masking glutathione scent
06:05 | Stability concerns & 2-week shelf life
07:23 | Paula’s Choice texture & film discussion
08:25 | The infamous “eggy with undertone of death” scent
10:16 | Clinical claims & before/after photos skepticism
12:04 | Niacinamide + tranexamic acid doing the heavy lifting
17:57 | Tulsa Wound serum: 2% glutathione, suspicious photos
21:03 | Abib serum: percentages, encapsulation, and clinical data

Product Shoutout: Double Play Retinol Face and Eye Treatment:
https://chemistconfessions.com/products/double-play-retinol-face-eye-treatment

Enrichment Content: Sunscreen Layering Guide https://www.youtube.com/watch?v=IQ0Dlb0WXvc

Do We Absorb Sunscreen Filters into Our Bloodstreams? https://chemistconfessions.com/blogs/controversy-corner-do-we-absorb-sunscreen-filters-into-our-bloodstreams 

Follow us: IG:   / chemist.confessions   INTERWEB: https://chemistconfessions.com/ TIKTOK: https://www.tiktok.com/@chemistconfes...

Skincare questions for the podcast? Leave your question in the comments and it could be featured in our next episode! #chemistconfessions #skincarescience #chemistconfessionspodcast #skincarehack

 

 

WE HEARD YOU! We explore the science behind one of the most requested and hyped ingredients skincare sector: glutathione. We break down what this "master antioxidant" actually is.

01:25 | What is Glutathione? Breaking down the tri-peptide 
01:54 | Why is it called the "Master Antioxidant"? 
02:43 | Mechanisms: Tyrosinase inhibition and skin whitening 
03:16 | The Stability Struggle: Why pH and temperature matter 
06:18 | Half-life study: How quickly does it degrade in your products? 
08:12 | Gold Standard Age Booster: Tactical hyperpigmentation tool 
08:40 | Does it actually work? Reviewing topical clinical studies 
12:35 | Study Deep Dive: 0.5% GSH vs. placebo on Indonesian women 
17:36 | Oxidized Glutathione (GSSG): Is a more stable version better?

Product Shoutout: Double Play Retinol Face and Eye Treatment:
https://chemistconfessions.com/products/double-play-retinol-face-eye-treatment

Enrichment Content: Sunscreen Layering Guide https://www.youtube.com/watch?v=IQ0Dlb0WXvc

Do We Absorb Sunscreen Filters into Our Bloodstreams? https://chemistconfessions.com/blogs/controversy-corner-do-we-absorb-sunscreen-filters-into-our-bloodstreams 

Follow us: IG:   / chemist.confessions   INTERWEB: https://chemistconfessions.com/ TIKTOK: https://www.tiktok.com/@chemistconfes...

Skincare questions for the podcast? Leave your question in the comments and it could be featured in our next episode! #chemistconfessions #skincarescience #chemistconfessionspodcast #skincarehack

We explore the science of skincare as we review five affordable, drugstore-priced arbutin products. In this episode, we break down everything from texture and clinical claims and ingredient lists of popular brands to help you find the right formula for your skin.

TIMESTAMPS: 
01:27 | Texture Analysis: Why is Arbutin so Sticky?
03:01 | Texture Face-Off: Oily vs. Dry Skin Reactions
04:48 | Is the Beauty of Joseon Serum a Moisturizer?
06:01 | Chemist Notes: Breaking Down the Cosrx Formula
06:57 | Analyzing Clinical Claims: Inner and Outer Melanin?
09:57 | Instrumental Measurements: Reducing Dark Spots
13:01 | Deep Dive: Beauty of Joseon Ingredients
14:56 | The Truth About "Pregnancy Safe" Marketing
16:25 | The Ordinary & Naturium: Simple Serum Breakdown

Product Shoutout: Double Play Retinol Face and Eye Treatment:
https://chemistconfessions.com/products/double-play-retinol-face-eye-treatment

Enrichment Content: Sunscreen Layering Guide https://www.youtube.com/watch?v=IQ0Dlb0WXvc

Do We Absorb Sunscreen Filters into Our Bloodstreams? https://chemistconfessions.com/blogs/controversy-corner-do-we-absorb-sunscreen-filters-into-our-bloodstreams 

Follow us: IG:   / chemist.confessions   INTERWEB: https://chemistconfessions.com/ TIKTOK: https://www.tiktok.com/@chemistconfes...

Skincare questions for the podcast? Leave your question in the comments and it could be featured in our next episode! #chemistconfessions #skincarescience #chemistconfessionspodcast #skincarehack

We are diving deep into the science of skincare to explore the role of Arbutin in treating hyperpigmentation. In this human conversation, we break down what exactly Arbutin is, analyze the existing data on its efficacy, and provide a comprehensive guide on what you should consider when shopping for these products.

 

 

Product Shoutout: Double Play Retinol Face and Eye Treatment:
https://chemistconfessions.com/products/double-play-retinol-face-eye-treatment

Enrichment Content: Sunscreen Layering Guide https://www.youtube.com/watch?v=IQ0Dlb0WXvc

Do We Absorb Sunscreen Filters into Our Bloodstreams? https://chemistconfessions.com/blogs/controversy-corner-do-we-absorb-sunscreen-filters-into-our-bloodstreams 

Follow us: IG:   / chemist.confessions   INTERWEB: https://chemistconfessions.com/ TIKTOK: https://www.tiktok.com/@chemistconfes...

Skincare questions for the podcast? Leave your question in the comments and it could be featured in our next episode! #chemistconfessions #skincarescience #chemistconfessionspodcast #skincarehack

In this episode, we take a deep dive into the world of K-beauty azelaic acid products. We explore the science behind three popular contenders—Anua, Purito, and medicube—while decoding their ingredient lists, analyzing clinical testing data, and discussing the tricky chemistry of azelaic acid solubility.  We provide a chemist’s perspective on how to choose the right formula for your skincare routine.

00:00 | Introducing K-Beauty Azelaic Acid Contenders  
00:02 | The "Ouch" Factor: Testing medicube’s Needle Technology 
00:04 | Sensation vs. Science: Do Spicules Improve Penetration?  
00:05 | Texture Breakdown: Puridose Oil Droplets vs. Anua Watery Serum  
00:08 | Decoding Ingredient Lists: Tea Tree Oil vs. Leaf Water 
 00:13 | Analyzing Anua’s Clinical Studies for Redness Reduction  
00:18 | Is 4-Week Acne Testing Actually Meaningful?  
00:23 | Bacterial Exosomes and the Future of Skincare Sourcing 
 00:29 | Chemist Corner: The Difficulty of Azelaic Acid Solubility  
00:32 | Final Verdict: Choosing Suspensions vs. Soluble Formulas

This week, we're starting our series on hyperpigmentation answering one of the most common questions many of us will encounter which is, "Is azelaic acid better than hydroquinone for my hyperpigmentation

00:00 | Introduction: 2026 Skincare Kickoff
03:45 | Investigating the PNAS Combination Study
08:12 | Deep Dive: Azelaic Acid vs. Hydroquinone
12:50 | The Challenge of Finding Full Research Papers
18:30 | Patient Compliance: The 16-Week Milestone
22:15 | Why Visual Improvements Take Time
27:00 | Analyzing Study Abstracts vs. Full Data
31:10 | Dual Therapy Overkill: 5% Concentration Discussion
31:50 | Motivation and Routine Consistency for Results

Product Shoutout:
Double Play Retinol
https://chemistconfessions.com/products/double-play-retinol-face-eye-treatment

Enrichment Content:
Chemists’ Guide to Choosing an Exfoliating Toner
https://chemistconfessions.com/blogs/how-to-choose-the-right-exfoliating-toner-for-your-skin

Follow us:
IG:   / chemist.confessions  
INTERWEB: https://chemistconfessions.com/
TIKTOK: https://www.tiktok.com/@chemistconfes...

Skincare questions for the podcast?
Leave your question in the comments and it could be featured in our next

 

The Chemist Confessions podcast year-end review is here!
We blitz through the 103 skincare products tested in 2025! We reveal our favorite and least favorite categories, discuss surprising finds like Hypochlorite Acid, and give our honest takes on individual products, including the Banana Boat Light as Air Sunscreen and the La Roche-Posay Cicaplast Sunscreen, and of course, Animal Corner!

Timestamps: 
00:00 | Welcome to Chemist Confessions Podcast & Year-End Review
01:07 | How Many Skincare Products Did We Test in 2025? (103 products!)
03:55 | Favorite Skincare Product Categories We Tested This Year
07:27 | What is Our Least Favorite Skincare Product Category?
10:07 | Why is K-Beauty C-Fu Dupe Testing Boring?
12:21 | Most Surprising Skincare Category: Cleansing Oils & Hypochlorite Acid
18:11 | Best Product of the Year: Banana Boat Light As Air Sunscreen Review
21:48 | Worst Product of the Year: La Roche-Posay Cicaplast Sunscreen Pill Test
25:54 | Most Surprising Product: What is A0X or 2X Intense?
28:17 | Are Cushion Foundations Good Sunscreens? Tarte Cushion Review

Products Discussed this 2025 Podcast Season *a small portion of your purchase through these links goes to feeding a chemist. https://shopmy.us/collections/1280514

Recommended 30 for 30 Sunscreens 2025 *a small portion of your purchase through these links goes to feeding a chemist. https://shopmy.us/collections/1766357

Product Shoutout: Blank Slate Gentle Gel Cleanser https://chemistconfessions.com/products/blank-slate-cleanser

Enrichment Content: Sunscreen Layering Guide https://www.youtube.com/watch?v=IQ0Dlb0WXvc

Do We Absorb Sunscreen Filters into Our Bloodstreams? https://chemistconfessions.com/blogs/controversy-corner-do-we-absorb-sunscreen-filters-into-our-bloodstreams 

Follow us: IG:   / chemist.confessions   INTERWEB: https://chemistconfessions.com/ TIKTOK: https://www.tiktok.com/@chemistconfes...

Skincare questions for the podcast? Leave your question in the comments, and it could be featured in our next episode! #chemistconfessions  #skincarescience  #chemistconfessionspodcast  #skincarehacks

We did a product head-to-head comparing occlusive balms, all with a petrolatum base! Following our beef tallow deep dive, we are breaking down the texture, transfer, price, and complex chemist notes of Vaseline, Aquaphor, CeraVe, Prequel, and our own Bon Voyage. Which formula is best for sensitive, compromised, dry, or oily skin, and why a simple formula isn't always best!

00:00 | Welcome to Chemist Confessions Podcast!
00:37 | What is an occlusive balm and why does petrolatum matter?
01:09 | Vaseline vs Aquaphor: Price and ingredient breakdown
03:25 | How does Vaseline’s texture change with application amount?
06:01 | Is Aquaphor better than Vaseline for lips and transfer resistance?
07:55 | Why is CeraVe Healing Ointment less shiny than other balms?
11:31 | How do dry vs oily skin types react to occlusive balms?
14:47 | Why does Vaseline have a drug facts label?
16:07 | Should you avoid complex balm formulas for compromised skin?
23:07 | Are occlusive balms temperature sensitive? Storage tips for warmer climates

Products Discussed this 2025 Podcast Season *a small portion of your purchase through these links goes to feeding a chemist. https://shopmy.us/collections/1280514

Recommended 30 for 30 Sunscreens 2025 *a small portion of your purchase through these links goes to feeding a chemist. https://shopmy.us/collections/1766357

Product Shoutout: Blank Slate Gentle Gel Cleanser https://chemistconfessions.com/products/blank-slate-cleanser

Enrichment Content: Sunscreen Layering Guide https://www.youtube.com/watch?v=IQ0Dlb0WXvc

Do We Absorb Sunscreen Filters into Our Bloodstreams? https://chemistconfessions.com/blogs/controversy-corner-do-we-absorb-sunscreen-filters-into-our-bloodstreams 

Follow us: IG:   / chemist.confessions   INTERWEB: https://chemistconfessions.com/ TIKTOK: https://www.tiktok.com/@chemistconfes...

Skincare questions for the podcast? Leave your question in the comments and it could be featured in our next episode! #chemistconfessions #skincarescience #chemistconfessionspodcast #skincarehack