Chemist Confessions

#135 4 Affordable Drugstore Moisturizers H2H

In 2025, the chemists want to tackle both the science and practical application of skincare. Following the ceramide deep dive, the chemists review 4 of the most popular drugstore moisturizers so you don’t have to, which include: Vanicream, CeraVe, Cetaphil, and La Roche Posay Lipikar. We discuss our thoughts on the texture and use experience from both the oily skin and dry skin perspective. 

#134: Which Ceramide is the Best For Your Skin?

The chemists are going down the ceramides rabbit hole again because many of you have asked, “Which ceramide is best?” The chemists explain the different types of ceramides and what the research says on which one you should be targeting in your skincare. 

#133: Prequel & Inkey's Ectoin Product H2H

In 2025, the chemists want to tackle both the science and practical application of skincare. Following the ectoin deep dive, the chemists review two ectoin products so you don’t have to. Products were chosen to showcase the diverse landscape of ectoin skicnare. This episode was recorded before the launch of Prequel’s latest Ectoin cream. We discuss our thoughts on the texture and use experience from both the oily skin and dry skin perspective. 

#132: Should you use ectoin in your routine?

Many of you asked about ectoin so the chemists went down the research rabbit hole. Ectoin is a new kid on the block with some surprising data in the skin barrier and hydration realm. The chemists talk about what it is, what it does for skin, and whether or not it’s better than niacinamide.

#131: 5 K-Beauty Toner Pads H2H

In 2025, the chemists want to tackle both the science and practical application of skincare. Following the pore care deep dive, the chemists review five toner pad products so you don’t have to. We discuss our thoughts on the texture and use experience from both the oily skin and dry skin perspective.

#130: Can You Shrink Pores with Skincare?

When strategizing how to tackle pores, the science is about as random as the skincare landscape. The chemists tackle the biology, the ingredients, and the skincare to try to make sense of what steps can actually make a meaningful difference to help reduce pore size. Can “glass”, “egg”, poreless skin actually achievable?

#129: Spicule Product H2H VT Reedle Shot 50 vs 100

In 2025, the chemists want to tackle both the science and practical application of skincare. Following the spicules deep dive, the chemists review the top two spicule (reedle) skincare products so you don’t have to. We discuss our thoughts on the texture and use experience from both the oily skin and dry skin perspectives.

#128: Is spicules worth trying in skincare?

Continuing our journey of diving into exciting, trendy new ingredients, this week, the chemists take a closer look at all the science behind spicule skincare. Though these prickly bits derived from marine sponges definitely have some interesting data, we still have more questions on how to best use spicules… Let’s jump in the rabbit hole!

#127: PDRN Products H2H Decode - Medicube vs VT

In 2025, the chemists want to tackle both the science and practical application of skincare. Following the PDRN deep dive, the chemists review the top two PDRN skincare products so you don’t have to. We discuss our thoughts on the texture and use experience from both the oily skin and dry skin perspective.

#126: Should You Use PDRN Skincare?

One of the most popular requests for us to decode is PDRN. Kbeauty continues to be at the center of trendy and exotic “new” skincare. This week, the chemists’ dive into PDRN, fragmented DNA derived from salmon sperm? They discuss what it is, how it ended up in our skincare, and if there’s any substantial evidence of PDRN’s benefits for skin. Let’s go down the rabbit hole!